mPES MicroKros Filter Modules

MicroKros Cutaway
Effective Length Side Port Spacing Housing ID Housing OD Inlet/Retentate ID Side Port ID Total Length
20 cm 19.6 cm 3.1 mm 4.6 mm 3 mm 4.3 mm 23 cm




Inlet/Outlet Ports:

Male Luer-Lok (MLL)

Permeate Ports:

Female Luer-Lok (FLL)



Designed for tangential flow filtration of small volumes ranging from 1 mL to 100 mL, single-use MicroKros® hollow fiber filters are the first efficient and practical tangential flow filtration device for characterizing a process for scale-up or filtration of small volumes in a laboratory setting. MicroKros® are available with MLL x FLL connections and 1 Effective Length.


mPES Applications

  • Concentrate proteins, peptides, enzymes, recombinant proteins, and/or diafiltration (Buffer Exchange) of these products
  • Depyrogenation Water / Buffers
  • Nano-Particle Coating, Buffer Exchange, Fractionating and/or Dewatering
  • Concentrate and diafilter albumin (nominal MW 67kd)
  • Concentration of monoclonal antibodies (155kd) and Buffer Exchange
  • Envelope and Non-Envelope Virus Concentration and Diafiltration
  • Clarification of cell lysates, viral expressed cultures to recover product in permeate
  • Concentration and washing of Insect, Bacterial and/or mammalian cells
  • SS (single stranded) or DS (double stranded) Nucleic Acids
  • Washing Latex, Polystyrene and other diagnostic particles to remove un-reactive / unbound drug substrates

Advantages of Single-Use TFF Filters

  • Reduces the number steps in a process
  • Increases Productivity
  • Reduces WFI water usage
  • Eliminates Cross-Contamination
  • Saves Money & Time

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