New Spectra/Por® Tube-A-Lyzer®
Disposable & Ready-to-Use
Spectrum's Tube-A-Lyzer is a ready-to-use, gentle separation device that combines convenience and disposability with the efficiency of dynamic dialysis to significantly increase the mass transfer rate and reduce the overall dialysis from 1-2 days to 12 hours. This self-contained, disposable device incorporates a semi-permeable membrane tubing that separates the sample chamber from the surrounding flow-through buffer chamber. The dry Biotech Grade Cellulose Ester (CE) membrane tubing is available in 6 MWCO's and the membrane-defined sample chamber is available in 2 volume sizes. The sample port provides easy access for loading, recovering and in-process testing. The housing is designed to be a flow-through dialysate chamber that can be connected to a buffer source and a waste collection vessel, or for discharging directly to drain. Tube-A-Lyzer is non-pyrogenic and can be sterilized (25 kGy gamma irradiation).

Mounted onto the support rack of the KrosFlo® Research I Pump System, Spectrum Laboratories part no. ACR1-U2S-01N (600 RPM), the Tube-A-Lyzer device can be operated as a single unit or in parallel when multiple units are combined using a coupling bracket (sold separately) into a multi-unit device. A second pump head can be mounted to the pump to operate two Tube-A-Lyzer units in parallel.

  • Faster dialysis; 4-12 hrs
  • Ready-to-Use and disposable: no preparation required
  • Easy sample loading, in-process testing and recovery
  • Maintains maximum concentration gradient
  • Prevents polarization and membrane fouling
  • Achieves higher sample purities
  • No heavy metals & sulfide contaminants
  • 95-98% Recovery
CE Membrane:
6 MWCO's (0.1-0.5, 3.5-5, 8-10, 20, 50 & 100 kD)
Dry packaged with 20% glycerin
Sample Chamber:
2 Volume sizes (8-10 ml & 25-30 ml)
Biotech Grade Cellulose Ester (CE) Membrane
Polycarbonate top and bottom piece Polyurethane potting
Female Luer-lok sample port
Polypropylene male Luer-lok cap
Buffer Chamber:
Polycarbonate housing
Polycarbonate end caps
6 mm (3/16 inch) hose-barb inlet / outlet ports
Dynamic Pump Rate:
10-20 ml/min (should be optimized for application)
Sample Chamber Volume Buffer Chamber Volume Total Length Total Dia. Membrane Effective Length Membrane Dia.
8-10 ml 50-55 ml 23 cm 2.2 cm 14-16 cm 1.0 cm
25-30 ml 120-130 ml 50 cm 2.2 cm 36-38 cm 1.0 cm
Spectra/Por Tube-A-Lyzer
Part Number BioTech Grade MWCO Sample Volume Qty Price
137002 CE 0.1-0.5 kD 8-10 ml 3/pkg
137042 CE 0.1-0.5 kD 25-30 ml 3/pkg
137004 CE 3.5-5 kD 8-10 ml 3/pkg
137044 CE 3.5-5 kD 25-30 ml 3/pkg
137006 CE 8-10 kD 8-10 ml 3/pkg
137046 CE 8-10 kD 25-30 ml 3/pkg
137008 CE 20 kD 8-10 ml 3/pkg
137048 CE 20 kD 25-30 ml 3/pkg
137009 CE 50 kD 8-10 ml 3/pkg
137049 CE 50 kD 25-30 ml 3/pkg
137010 CE 100 kD 8-10 ml 3/pkg
137050 CE 100 kD 25-30 ml 3/pkg
Tube-A-Lyzer Accessories
Part No. Description Price (US$)
137110 Tube-A-Lyzer Sample Loading Kit (includes 3 syringes (30cc), 3 dispensing tips & 2 coupling brackets)
137110 Replacement Dispensing Tips, 12/pkg
ACTU-E16-25N Extended Life Silicone Tubing, 1/8 in. (3.1 mm) ID, 25 ft (7.6 m)
Use a credit card on-line and get a 10% discount! Details here.
Dynamic Dialysis Applications:
  • Purification of Labile Proteins
  • Dialysis of Viscous Liquids
  • Desalting
  • Buffer & pH Change
  • Concentration of Antibodies
  • Binding Studies
  • Temperature Regulated Dialysis
  • Remove Oligosaccharides
  • Flow Dialysis / Batch Analysis
  • Tissue Culture Extract Purification


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